Per- and polyfluoroalkyl substances (PFAS) are subject to regulation worldwide due to their widespread use, environmental persistence, and potential to cause adverse health effects. Many government bodies have established restrictions or bans for PFAS in consumer products to protect human health and the environment. However, regulatory approaches vary among different countries and regions, which presents companies with several compliance challenges and exposes them to risk within their supply chains. By utilizing risk mitigation strategies and employing the right tools, companies can streamline PFAS identification and reporting.